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Italy Grand Loop

A 10-day driving loop around Italy, keeping each day simple: one big, top-tier sight, then time to actually enjoy the place instead of sprinting.

10days
11stops
394km
DAY01

Depart → Colosseum

Overnight in Colosseum
  1. 09:00
    Depart· start
  3. 09:30
    Colosseum· overnightMust-see
Accommodation
Rome historic center
DAY02

Uffizi Gallery

Overnight in Uffizi Gallery
  1. 12:30
    Uffizi GalleryMust-see
Accommodation
Florence Santa Maria Novella / Oltrarno area
DAY03

Depart → St. Mark's Basilica

Overnight in St. Mark's Basilica
  1. 08:30
    Depart· start
  3. 12:30
    St. Mark's Basilica· overnightMust-see
Accommodation
Venice island or Mestre
DAY04

Depart → Duomo di Milano

Overnight in Duomo di Milano
  1. 09:00
    Depart· start
  3. 13:00
    Duomo di Milano· overnightMust-see
Accommodation
Milan Brera / Duomo edge
DAY05

Depart → Cinque Terre National Park

58 km · 1h 4m driving · Overnight in Cinque Terre National Park
  1. 08:30
    Depart· start
  2. 58 km · 1h 4m
  3. 12:30
    Cinque Terre National Park· overnightMust-see
Accommodation
La Spezia or Levanto
DAY06

Depart → San Gimignano Historic Centre

55 km · 1h 3m driving · Overnight in San Gimignano Historic Centre
  1. 09:00
    Depart· start
  2. 55 km · 1h 3m
  3. 12:00
    San Gimignano Historic Centre· overnightMust-see
Accommodation
San Gimignano countryside or Siena outskirts
DAY07

Depart → Pompeii Archaeological Park

2.7 km · 10m driving · Overnight in Pompeii Archaeological Park
  1. 08:00
    Depart· start
  2. 2.7 km · 10m
  3. 14:00
    Pompeii Archaeological Park· overnightMust-see
Accommodation
Pompeii / Sorrento area
DAY08

Depart → Amalfi Coast

1.9 km · 7m driving · Overnight in Amalfi Coast
  1. 09:00
    Depart· start
  2. 1.9 km · 7m
  3. 11:00
    Amalfi Coast· overnightMust-see
Accommodation
Amalfi Coast or Sorrento
DAY09

Depart → Sassi di Matera

276 km · 3h 5m driving · Overnight in Sassi di Matera
  1. 08:30
    Depart· start
  2. 276 km · 3h 5m
  3. 13:00
    Sassi di Matera· overnightMust-see
Accommodation
Matera old-town edge
DAY10

Depart → Vatican Museums

  1. 08:00
    Depart· start
  3. 14:30
    Vatican MuseumsMust-see
Accommodation
Rome historic center or Prati
Heads Up
  • Reserve timed tickets for the Colosseum, Uffizi, St. Mark’s Basilica, Duomo rooftop, Pompeii, and Vatican Museums where available.
  • Keep the car outside historic centers whenever possible because ZTL zones are heavily enforced.
  • For Venice and Cinque Terre, park once and move around on foot or local transport; it will save your nerves.