Italian Grand Tour: Rome to Venice

Ten days is the perfect amount of time to hit the "Big Three" while squeezing in some Tuscan countryside magic. We're driving the middle leg to give you that classic rolling-hill experience.

10days
32stops
509drive km
Day 1: Eternal City Beginnings
18min · 4.2km3 stops
Colosseum
09:00
11min · 3.0km
Pantheon
13:30
7min · 1.2km
Piazza Navona
16:30
Day 2: Vatican Treasures
20min · 6.3km3 stops
Vatican Museums
08:30
14min · 4.8km
St. Peter's Basilica
13:00
6min · 1.4km
Castel Sant'Angelo
16:00
Day 3: Roman Fountains & Piazzas
1h 14min · 65km3 stops
Trevi Fountain
10:00
1h 7min · 64km
Spanish Steps
14:00
7min · 1.3km
Villa Borghese
17:30
Day 4: The Road to Tuscany
3h 8min · 207km4 stops
Depart Rome
09:00
1h 41min · 123km
Civita di Bagnoregio
11:30
1h 25min · 83km
Val d'Orcia
15:00
2min · 0.5km
Pienza
17:30
Day 5: Siena’s Medieval Heart
1h 1min · 54km3 stops
Piazza del Campo
10:00
57min · 53km
Duomo di Siena
13:30
4min · 0.8km
Monteriggioni
16:00
Day 6: Renaissance Arrival
1h 27min · 81km3 stops
San Gimignano
10:00
36min · 28km
Piazzale Michelangelo
14:00
51min · 53km
Ponte Vecchio
17:00
Day 7: Florentine Art
13min · 3.1km3 stops
Uffizi Gallery
09:00
1min · 0.3km
Cathedral of Santa Maria del Fiore
13:00
12min · 2.8km
Accademia Gallery
16:00
Day 8: Leaning Towers & Fast Trains
1h 26min · 89km4 stops
Leaning Tower of Pisa
09:30
1h 18min · 86km
Pisa Centrale
13:00
8min · 2.5km
Venezia Santa Lucia
15:30
Grand Canal
17:30
Day 9: Venetian Islands
3 stops
St. Mark's Square
10:00
Burano
14:00
Rialto Bridge
17:00
Day 10: The Floating City
3 stops
Doge's Palace
10:00
Santa Maria della Salute
14:00
Venice
16:30
Heads Up
  1. Buy a 'Venezia Unica' pass for the water buses if you plan to visit the islands; individual tickets are pricey.
  2. In Florence and Rome, book your museum slots at least 2-3 months out!

Italian Grand Tour: Rome to Venice

A comprehensive journey through the heart of Italy, covering iconic cities, rolling Tuscan landscapes, and the historic canals of Venice.

Rome → Civita di Bagnoregio → Val d'Orcia → Pienza → Siena → San Gimignano → Florence → Pisa → Venice

  1. Eternal City Beginnings

    Grab an early entry slot to beat the heat and the crowds. Walking through the tiers where gladiators once stood is heavy, but incredible. Give yourself at least 3 hours here and at the Forum next door.

    • Colosseum

      Grab an early entry slot to beat the heat and the crowds. Walking through the tiers where gladiators once stood is heavy, but incredible. Give yourself at least 3 hours here and at the Forum next door.

    • Pantheon

      Grab a quick pizza al taglio nearby and walk into the best-preserved building from Ancient Rome. Look up at the oculus; if it rains, the floor drains still work after 2,000 years.

    • Piazza Navona

      This is the spot for people-watching. The fountains are masterpieces, and the street performers keep the energy high as the sun starts to dip.

  2. Vatican Treasures

    Vatican Treasures (0km, 0h drive)

    • Vatican Museums

      Pre-book these months in advance or you'll spend half your day in line. The Sistine Chapel is the finale, but the map gallery is actually my favorite part.

    • St. Peter's Basilica

      It’s free to enter, but the security line moves slow. Climb the dome (cupola) if your legs are up for it; the view of the square is the best in the city.

    • Castel Sant'Angelo

      Walk across the bridge lined with angels. The terrace at the top offers a killer view of the Tiber River as the city lights start to flicker on.

  3. Roman Fountains & Piazzas

    It’s a cliché for a reason. Toss your coin in early before the midday selfie-stick swarm reaches its peak.

    • Trevi Fountain

      It’s a cliché for a reason. Toss your coin in early before the midday selfie-stick swarm reaches its peak.

    • Spanish Steps

      Do some window shopping on Via dei Condotti nearby, then rest your feet at the base of the steps (remember, no sitting on the actual steps anymore or the police will whistle at you!).

    • Villa Borghese

      Rent a rowboat on the little lake or just wander the gardens. It’s the "green lung" of Rome and the perfect sunset spot.

  4. The Road to Tuscany

    Pick up your rental car near Termini or the airport to avoid the ZTL (restricted driving zones) in the center.

    • Depart Rome

      Pick up your rental car near Termini or the airport to avoid the ZTL (restricted driving zones) in the center.

    • Civita di Bagnoregio

      This is the "dying city" perched on a crumbling plateau. You have to walk across a long pedestrian bridge to get in. It’s hauntingly beautiful and very quiet.

    • Val d'Orcia

      This is the "Gladiator" landscape—cypress trees and rolling gold hills. Stop by the Vitaleta Chapel for that iconic photo.

    • Pienza

      A tiny Renaissance town famous for Pecorino cheese. The smell of truffle and aged cheese hits you the moment you walk through the gates.

  5. Siena’s Medieval Heart

    Siena’s Medieval Heart

    • Piazza del Campo

      The shell-shaped main square where they hold the Palio horse race. Grab a gelato and sit on the warm bricks like a local.

    • Duomo di Siena

      The striped marble interior is mind-blowing. Don't skip the Piccolomini Library inside; the frescoes look like they were painted yesterday.

    • Monteriggioni

      A perfectly circular walled village on a hill. You can walk the ramparts for views of the vineyards below.

  6. Renaissance Arrival

    The "Manhattan of the Middle Ages" because of its stone towers. Climb the Torre Grossa for a panoramic view of the Tuscan sprawl.

    • San Gimignano

      The "Manhattan of the Middle Ages" because of its stone towers. Climb the Torre Grossa for a panoramic view of the Tuscan sprawl.

    • Piazzale Michelangelo

      Drive into Florence and head straight here. It’s the classic postcard view of the Duomo and the Arno River.

    • Ponte Vecchio

      Drop the car at a garage (Florence is a nightmare to drive in) and walk across the bridge of gold shops before the jewelers close up.

  7. Florentine Art

    Florentine Art (0km, 0h drive)

    • Uffizi Gallery

      Say hi to Botticelli’s *Venus*. Even if you aren't an "art person," the architecture and the history here are staggering.

    • Cathedral of Santa Maria del Fiore

      Better known as the Duomo. The green and white marble facade is dizzying. Even if you don't go in, walk the entire perimeter.

    • Accademia Gallery

      You’re here for one thing: Michelangelo’s *David*. He’s much bigger in person than you expect.

  8. Leaning Towers & Fast Trains

    It’s an hour drive from Florence. Do the cheesy photo, admire the Baptistery, and then head to the train station.

    • Leaning Tower of Pisa

      It’s an hour drive from Florence. Do the cheesy photo, admire the Baptistery, and then head to the train station.

    • Pisa Centrale

      Drop the rental car here.

    • Venezia Santa Lucia

      Take the train from Pisa (usually via Florence) to Venice. The moment you walk out of Santa Lucia station and see the Grand Canal, your jaw will drop.

    • Grand Canal

      Take the Line 1 water bus down the Grand Canal to your hotel. It's the best "cheap" tour of the city's palaces.

  9. Venetian Islands

    Get here early to see the Basilica and the Doge's Palace before the cruise ship crowds arrive.

    • St. Mark's Square

      Get here early to see the Basilica and the Doge's Palace before the cruise ship crowds arrive.

    • Burano

      Take the ferry out to the island of neon-colored houses. It’s a photographer’s dream. Grab some bussolai cookies while you're there.

    • Rialto Bridge

      Head back to the main island to watch the gondolas pass under the bridge as the sun sets.

  10. The Floating City

    The Floating City

    • Doge's Palace

      Walk across the Bridge of Sighs from the inside. The history of the Venetian Republic is fascinatingly dark.

    • Santa Maria della Salute

      A massive domed church at the entrance of the Grand Canal. It’s quieter than St. Mark’s and very peaceful.

    • Venice

      It’s expensive (fixed rates, usually €80-100), but doing it on your last evening through the narrow back canals is the perfect goodbye to Italy.